单细胞测序技术服务 单细胞全转录组测序 |
NGS测序技术服务 DRIP-seq |
基因芯片技术服务 Small RNA表达芯片 Small RNA修饰芯片 m6A单碱基分辨率芯片 mRNA&lncRNA表观转录组芯片 circRNA表观转录组芯片 |
NGS测序技术服务 RNA m6A甲基化测序(MeRIP Seq) |
LC-MS mRNA碱基修饰检测 tRNA碱基修饰检测 |
PCR技术服务 MeRIP-PCR技术服务 m6A绝对定量RT-PCR技术服务 m6A单碱基位点PCR(MazF酶切法)技术服务 |
基因芯片技术服务 DNA甲基化芯片 DNA羟甲基化芯片 ChIP-chip |
NGS测序技术服务 DNA甲酰基胞嘧啶(5fc)修饰测序 DNA 5hmC 测序(化学法) DNA甲基化测序 DNA羟甲基化测序 染色质免疫共沉淀测序 |
PCR技术服务 MeDIP-qPCR hMeDIP-qPCR ChIP-qPCR |
蛋白相对定量 TMT标记定量技术 非标定量技术 |
蛋白修饰 TMT标记定量磷酸化 非标定量磷酸化 |
RNA/蛋白-蛋白相互作用 HyPro靶RNA临近标记技术 RNA-蛋白相互作用 蛋白-蛋白相互作用 |
METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis , Molecular Cancer . 2022NEW!
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by
upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer . Molecular
Cancer . 2022NEW!
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its
stability to facilitate nasopharyngeal carcinoma growth and metastasis . Cell
Death & Differentiation . 2022NEW!
METTL3 promotes colorectal carcinoma progression by regulating the m6A–CRB3–Hippo axis . Journal of Experimental & Clinical Cancer Research . 2022NEW!
m6A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels . Cancer Communications . 2022NEW!
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression . Oncogene . 2022NEW!
The Combined Effects of circRNA Methylation Promote Pulmonary Fibrosis . American Journal of Respiratory Cell and Molecular Biology . 2022NEW!
ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1 . Theranostics . 2021
RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent . Journal of Experimental & Clinical Cancer Research . 2021
ALKBH5-mediated m6A mRNA Methylation Governs Human Embryonic Stem Cell Cardiac Commitment . Molecular Therapy-Nucleic Acids . 2021
ALKBH5 suppresses tumor progression via an m 6 A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma . Cell Death & Disease . 2021
RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes . Cell Death & Disease . 2021
The potential roles of m6 A modification in regulating the inflammatory response in microglia . Journal of Neuroinflammation . 2021
The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N 6-methyladenosine methylation of Parp10 mRNA . Nature Cell Biology . 2020
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer " . Molecular cancer . 2020
NADP modulates RNA m 6 A methylation and adipogenesis via enhancing FTO activity . Nature Chemical Biology . 2020
N6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1-Regulated Astrocyte Dysfunction and Depressive-like Behaviors. . Biological Paychiatry . 2020
SIRT1 regulates N6‐methyladenosine RNA modification in hepatocarcinogenesis by inducing RANBP2‐dependent FTO SUMOylation . Hepatology . 2020
m6A methylation of precursor-miR-320/RUNX2 controls osteogenic potential of bone marrow-derived mesenchymal stem cells . Molecular Therapy-Nucleic Acids . 2019
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3 . Molecular Cancer . 2019
METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance. . Gut . 2019
Genome-wide screening of altered m6A-tagged transcript profiles in the hippocampus after traumatic brain injury in mice . Epigenomics . 2019